论文部分内容阅读
目的:观察主动呼吸循环技术对急性加重期慢性阻塞性肺疾病(AECOPD)患者的治疗效果,评价其临床应用价值。方法:选取2013年1月至2015年5月在我院治疗的100例AECOPD患者为研究对象,随机分为对照组和观察组,每组50例,对照组给予呼吸科常规治疗,观察组在此基础上辅以主动呼吸循环技术。经过1个周期的治疗后,比较两组患者肺功能、血常规及动脉血气分析指标以及排痰量的差异。结果:治疗前两组患者的肺功能相关指标差异无统计学意义,治疗后两组患者的肺功能均有所改善,但观察组患者改善更为明显;两组患者治疗前白细胞计数(WBC)、中性粒细胞比例(NEU%)、血红蛋白(Hb)、C反应蛋白(CRP)和血清白蛋白(ALB)差异无统计学意义,治疗后两组患者的WBC、NEU%、Hb和CRP含量均降低,且治疗组WBC、NEU%和CRP含量明显低于对照组,Hb含量明显高于对照组;两组患者ALB水平无明显变化。治疗后两组患者的动脉血气分析指标均有所改善,且观察组较对照组改善更明显;治疗前两组患者不同等级AECOPD患者24 h痰量无明显差异,治疗后观察组Ⅱ~Ⅳ级患者痰量较对照组明显减少,差异有统计学意义,而两组AECOPDⅠ级患者的痰量无明显差异。结论:主动呼吸循环技术对AECOPD有较好的疗效,可明显改善患者的肺功能和动脉血气指标,尤其对中重度AECOPD患者有较好的治疗效果。
Objective: To observe the therapeutic effect of active respiratory circulation in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and evaluate its clinical value. Methods: One hundred patients with AECOPD treated in our hospital from January 2013 to May 2015 were selected and randomly divided into control group and observation group, 50 cases in each group. The control group was given routine treatment of respiratory department, This is supplemented by active breathing cycle technology. After one cycle of treatment, the lung function, blood routine and arterial blood gas analysis index and sputum volume difference were compared between the two groups. Results: There was no significant difference in the indexes of pulmonary function between the two groups before treatment. The lung function of both groups improved after the treatment, but the improvement in the observation group was more obvious. Before treatment, the white blood cell count (WBC) , Neutrophil ratio (NEU%), hemoglobin (Hb), C reactive protein (CRP) and serum albumin (ALB) were not statistically different between the two groups after treatment WBC, NEU%, Hb and CRP levels , And the content of WBC, NEU% and CRP in the treatment group were significantly lower than those in the control group, and the content of Hb in the treatment group was significantly higher than that in the control group. There was no significant change in ALB level in the two groups. After treatment, arterial blood gas analysis index of both groups improved, and the observation group improved more obviously than the control group. There was no significant difference in 24 h sputum volume of AECOPD patients between the two groups before treatment, and Ⅱ ~ Ⅳ level Patients with sputum volume was significantly reduced compared with the control group, the difference was statistically significant, but the two groups AECOPD Ⅰ level sputum volume was no significant difference. Conclusion: The active respiratory cycle technique has a good curative effect on AECOPD, which can significantly improve the pulmonary function and arterial blood gas index, especially for moderate and severe AECOPD patients.