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目的分析预防性应用抗菌药物对剖宫产术后患者抗感染的效果,探讨如何有效降低剖宫产术后感染率。方法选取2014年1月至2016年5月广东医学院附属深圳南山医院收治的剖宫产产妇62例,分成研究组(给予预防性抗菌药物)和对照组(未给予预防性抗菌药物),每组31例。对产妇的白细胞计数、排气时间、感染率、C反应蛋白(C-reactive protein,CRP)、清蛋白、前清蛋白等指标进行观察和比较。结果(1)研究组产妇的白细胞计数和排气时间均明显低于对照组(P<0.05),研究组无感染发生,明显低于对照组(12.90%)(P<0.05);(2)术前两组患者的CRP、清蛋白、前清蛋白等炎症因子水平比较,差异无统计学意义(P﹥0.05);术后研究组患者的CRP水平低于对照组,清蛋白和前清蛋白水平高于对照组(P<0.05)。结论给予预防性应用抗菌药物可以有效地降低产妇剖宫产术后感染率,控制产妇的炎症因子水平,是临床实践的理想选择之一。
Objective To analyze the anti-infective effect of prophylactic antibacterials in patients after cesarean section and to explore how to effectively reduce the infection rate after cesarean section. Methods From January 2014 to May 2016, 62 cases of cesarean section women from Shenzhen Nanshan Hospital Affiliated to Guangdong Medical College were divided into study group (given preventive antibacterials) and control group (no preventive antibacterials were given) Group of 31 cases. The maternal white blood cell count, exhaust time, infection rate, C-reactive protein (CRP), albumin, prealbumin and other indicators were observed and compared. Results (1) The leucocyte count and time of excretion in the study group were significantly lower than those in the control group (P <0.05). There was no infection in the study group, which was significantly lower than that in the control group (12.90%) (P <0.05) The levels of CRP, albumin, prealbumin and other inflammatory factors in the two groups before surgery were not significantly different (P> 0.05). The postoperative CRP levels in study group were lower than those in control group, albumin and prealbumin The level was higher than the control group (P <0.05). Conclusion The prophylactic use of antimicrobial agents can effectively reduce the post-cesarean section infection rate and control the level of inflammatory cytokines in maternal women, which is one of the ideal choices in clinical practice.