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本文对比分析了正常人和结直肠癌患者的血清的拉曼光谱。选择拉曼峰信息和荧光背景信息作为参数进行统计分析。用主成分回归(Principal component regression,PCR)和线性辨别分析(linear discriminant analysis,LDA)对所选参数进行分析以观察这些参数对光谱的代表性,得到了87.50%的准确率。得到的结论为,本实验所选参数能较好保留原始光谱信息,血清的拉曼光谱具有诊断结直肠癌的潜力。
This article compares the Raman spectra of serum from normal and colorectal cancer patients. Select Raman peak information and fluorescence background information as a parameter for statistical analysis. The selected parameters were analyzed using principal component regression (PCR) and linear discriminant analysis (LDA) to observe the spectral representation of these parameters with an accuracy of 87.50%. The conclusion obtained is that the parameters selected in this experiment can better preserve the original spectral information, and the serum Raman spectrum has the potential of diagnosing colorectal cancer.