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据热带医学教科书记载,班氏丝虫病曾在美国南卡罗来纳州查尔斯顿市流行,1930年后消失。丝虫病传入该市系由于早期奴隶贸易市场开放,从非洲来的奴隶输进传染源,加之当地气候环境适于致倦库蚊孳生,导致丝虫病传播,并蔓延到周围几个城市。临床表现主要为象皮腿和乳糜尿,当时尚无特异性诊疗办法,直到1872年Lewis从血片中查见班氏微丝蚴,1880年Manson进一步证实为夜间周期型班氏丝虫。1884年Guiteras从居住在Key West的4名古巴人血中发现班氏微丝蚴,不久,他又首次证实查尔斯顿当地人感染了丝虫,此后该市经血检证实的病
According to tropical medical textbooks, Bancroftian filariasis was endemic to Charleston, South Carolina and disappeared after 1930. Introduction of Filariasis into the City Due to the opening up of the early slave trade market, slaves from Africa are fed into sources of infection, and the local climate and environment are suitable for breeding Culex pipiens. This causes the spread of filariasis and spread to several surrounding cities . Clinical manifestations were mainly leg and chyluria. At that time, there was no specific diagnosis or treatment. Until 1872, Lewis examined the Banczalver’s microfilaria in blood films. In 1880, Manson further confirmed that it was a nighttime bancroftian. In 1884, Guiteras found Benfica’s microfilaria in four Cuban bloods living in Key West. It was not until long that he later confirmed that the natives of Charleston were infected with filariasis, and the city was confirmed by blood tests