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[文献来源]CHALABI M,FANCHI L F,DIJKSTRA K K,et al.Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers[J].Nat Med,2020,26(4):566-576.摘要:PD-1联合CTLA-4阻滞剂对晚期错配修复蛋白(MMR)缺失(dMMR)型结直肠癌患者的治疗非常有效,但对MM