进行性系统性硬皮病Progressive SystemicSclerosis。简称PSS)较为少见,该病是一种自身免疫性结缔组织性疾病,它可累及全身多个器官。既往文献对皮肤、肌肉、关节及消化道病变报道较多,然而对肺的受累损害报道甚少。本文拟对我院1970～1989年间收治的22例PSS 患者临床资料作一分析,并对其引起的肺部损害予以讨论。 Progressive Systemic Sclerosis. Referred to as PSS) is relatively rare, the disease is an autoimmune connective tissue disease, which can affect multiple organs throughout the body. Previous literature on the skin, muscle, joint and gastrointestinal lesions reported more, but little involvement of lung damage reported. This article intends to analyze the clinical data of 22 patients with PSS admitted to our hospital from 1970 to 1989 and to discuss the lung damage caused by them.