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目的:探讨血必净联合血液灌流用于早期治疗急性百草枯中毒的疗效。方法:选取2013年3月至2016年3月我院收治的急性百草枯中毒患者30例作为研究对象,随机将其分成对照组和观察组,每组15例;对照组患者在常规治疗的基础上采用血液灌流进行治疗,观察组在对照组的基础上联合血必清进行治疗,对比分析两组患者的酶学指标以及血肌酐指标的改善情况、治疗的疗效及安全性。结果:经过治疗,两组患者的酶学指标以及血肌酐指标都有比较显著的下降,观察组的指标明显低于对照组;观察组的治愈率为80.00%显著优于对照组66.67%;观察组的病死率为20.00%显著低于对照组33.33%。两组比较差异值P<0.05,均有统计学意义。结论:血必净联合血液灌流用于急性百草枯中毒的早期治疗具有比较满意的疗效,大大低降低了患者的病死率,值得临床借鉴。
Objective: To investigate the effect of Xuebijing combined with hemoperfusion on the early treatment of acute paraquat poisoning. Methods: From March 2013 to March 2016, 30 acute paraquat poisoning patients admitted to our hospital were selected as study subjects and randomly divided into control group and observation group with 15 cases in each group. Patients in control group were treated on the basis of routine treatment On the basis of the control group, the patients in the observation group were treated with Xuebai Qing, and the enzymology indexes, the improvement of serum creatinine index, the curative effect and safety of the treatment were compared and analyzed. Results: After treatment, the enzymological indexes and serum creatinine indexes decreased significantly in both groups, and the indexes in the observation group were significantly lower than those in the control group. The cure rate in the observation group was 80.00%, significantly higher than that in the control group (66.67%). The case fatality rate of 20.00% was significantly lower than the control group 33.33%. The difference between the two groups P <0.05, were statistically significant. Conclusion: Xuebijing combined with hemoperfusion for the early treatment of acute paraquat poisoning has a satisfactory effect, greatly reducing the mortality of patients, it is worth learning from.