论文部分内容阅读
１９８８年至１９９２年间曾对６４例ＤｕｋｅｓＢ、Ｃ和Ａ３期直肠癌患者进行了术前术后清栓酶导管升压热疗．每次０．５单位、每日一次，术前一疗程，术后两疗程：每疗程１５至２０天，停３至５天重复另一疗程：并随机选择同时期、情况基本相同和未进行术前术后化疗和清栓酶治疗的直肠癌患者６４例作为对照组，术后随访２至５年。术前术后清栓酶导管升压热疗组术后局部复发率为１４％、远处转移率１１％；而对照组术后局部复发率为２７％、远处转移率为２５％，两者皆有显著差异（Ｐ＜０．０５）。升压、热疗使清栓酶的活性作用提高１０至３０倍。因此．作者认为对ＤｕｋｅｓＢ、Ｃ和Ａ３直肠癌病人、在术前术后应进行清栓酶导管升压热疗，以减少术后局部复发和远处转移。
Between 1998 and 1992, 64 patients with Dukes B, C and A3 colorectal cancer were treated with preoperative and postoperative thrombectomy catheter hyperthermia. 0.5 units per day, once daily, one course before surgery, two courses after surgery: 15 to 20 days per course of treatment, 3 to 5 days rest for another course of treatment: randomly selected at the same time, the conditions are basically the same and not performed 64 patients with rectal cancer who underwent preoperative and postoperative chemotherapy and erythromycin administration were used as controls and were followed up for 2 to 5 years. The local recurrence rate was 14% and the distant metastasis rate was 11% in the hyperthermia group before and after surgery. The rate of local recurrence after surgery was 27% in the control group, and the distant metastasis rate was 25%. All had significant differences (P<0.05). Boosting and hyperthermia increase the activity of the hydratase by 10 to 30 times. therefore. The authors believe that in patients with Dukes B, C, and A3 rectal cancer, preoperative and postoperative thrombolytic catheter hyperthermia should be performed to reduce postoperative local recurrence and distant metastasis.