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自1926年 Cordes 首次报告4例患者服用扑疟喹啉(Pamaquine)发生急性溶血以来,已陆续发现数十种药物对敏感个体可诱发溶血。1956年,Carson等研究证实,溶血发生原因与患者红细胞中缺乏葡萄糖-6-磷酸脱氢酶
Since Cordes’ first report of 4 patients taking paralyquamil in acute hemolysis in 1926, dozens of drugs have been found to induce hemolysis in sensitive individuals. In 1956, Carson and other studies confirmed that the cause of hemolysis and erythrocyte patients lack the glucose-6-phosphate dehydrogenase