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吉尔伯综合征(Glbert’sSyndome)的遗传基础还未确定。常见的轻型高胆红素血症有时以周期性黄胆形式出现。肝胆红素UDP-葡萄糖醛酸基转移酶(UGT)浓度的降低与此综合征有关。本文作者在苏格兰人群中,检查了UGTI’1基因的变异及血清胆红素浓度,研究了胆红素UGT基因启动子的?
The genetic basis of Gilbert’s Syndome has not been established. Common light hyperbilirubinemia sometimes appears in the form of periodic yellow bile. The decrease in hepatic bilirubin UDP-glucuronosyltransferase (UGT) concentration is associated with this syndrome. In the Scottish population, the authors examined the variation of UGTI’1 gene and serum bilirubin concentrations and studied the promoter of the UGT gene of bilirubin.