先天性甲状腺激素合成障碍,可认为是与激素合成有关的酶先天异常的基因病。大部分与其他先天代谢异常症相同,取常染色体劣性遗传形式。合成过程的障碍如果严重,则引起甲状腺机能低下,同时,TSH分泌增加,甲状腺肿大。即这也是一种先天性甲低症(克汀病),别名叫做甲状腺肿性克汀病(Goitrous cretinism)。另方面,合成过 Congenital thyroid hormone synthesis disorders, can be considered and hormone synthesis related to genetic abnormalities inherent in the enzyme. Most of the same with other congenital metabolic disorders, take the genetic form of autosomal dominant. If the obstacles to the synthesis process are serious, the hypothyroidism is caused. At the same time, the TSH secretion is increased and the goiter is enlarged. This is also a congenital hypothyroidism (cretinism), alias called goitrous cretinism (Goitrous cretinism). On the other hand, synthesized