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吡喹酮治疗寄生虫病的剂量仍在不断地修正。Taylor等(1988)认为20,30和40mg/kg单剂对埃及血吸虫病或30和40mg/kg单剂对曼氏血吸虫病的治愈率无明显差别。Bunnag和Harinasuta(1981)提出将泰国治疗后睾吸虫病单剂有效剂量从75mg/kg减为40mg/kg。Groll(1980)和Rezende(1983)建议治疗猪带绦虫病和牛带绦虫病的单剂剂量为5mg/kg或10mg/kg;但晚近,Pawlowski等在波兰波兹南治疗牛带绦虫病,肯定5mg/kg和2.5mg/kg单剂有满意疗效。因而,有必要就其剂量作一回顾与讨论,以探讨吡喹
The dose of praziquantel for the treatment of parasitic diseases is still constantly being revised. Taylor et al. (1988) concluded that there is no significant difference in the cure rates of schistosomiasis japonica or single doses of 30 and 40 mg / kg for 20 and 30 mg / kg single dose of Schistosoma mansoni. Bunnag and Harinasuta (1981) proposed reducing the single-dose effective dose of post-treatment clonorchiasis from 75 mg / kg to 40 mg / kg in Thailand. A single dose of 5 mg / kg or 10 mg / kg recommended by Groll (1980) and Rezende (1983) for the treatment of Taenia taeniasis and Taenias taiga was recently treated by Pawlowski et al in Poznan, Poland, affirming 5 mg / kg and 2.5mg / kg single dose have a satisfactory effect. Therefore, it is necessary to make a review of its dose and discussion to explore praziquantel