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目的了解我国(未包括香港、澳门特别行政区和台湾地区,下同)现阶段育龄期妇女乙型肝炎(乙肝)病毒表面抗原[Hepatitis B Virus(HBV)Surface Antigen,HBsAg]、抗乙肝病毒表面抗原抗体(Antibody to HBsAg,Anti-HBs)、乙肝病毒e抗原(HBV e Antigen,HBeAg)、抗乙肝病毒e抗原抗体(Antibody to HBeAg,Anti-HBe)的流行情况。方法用血清流行病学分析方法,在31个省(自治区、直辖市)的160个国家疾病监测点,多阶段随机抽取1～59岁常住人口,采集调查对象静脉血4ml,统一检测HBsAg、Anti-HBs。HBsAg阳性者再进一步检测HBeAg和Anti-HBe;对15～49岁育龄期妇女进行HBsAg及HBeAg流行状况分析。结果经加权调整后,我国育龄期妇女HBsAg流行率为6.61%,Anti-HBs流行率为47.33%。在HBsAg阳性育龄期妇女中,HBeAg流行率为23.51%,Anti-HBe流行率为75.54%。育龄期妇女HBsAg流行率在地区、城乡、民族和文化程度之间的差异无统计学意义,但20～24岁、30～34岁两组育龄期妇女,HBsAg流行率略高于全国育龄期妇女总HBsAg流行率。结论我国现阶段,育龄期妇女HBsAg流行率为6.61%,略低于全国一般水平。其中23.51%的HBsAg阳性妇女为HBsAg及HBeAg双阳性。
Objective To understand the prevalence of hepatitis B virus surface antigen (HBsAg), hepatitis B virus surface antigen (HBsAg) in women of childbearing age in our country (excluding Hong Kong, Macao Special Administrative Region and Taiwan) Antibody to HBsAg, Anti-HBs, HBeAg and Anti-HBe. Methods Serum epidemiological analysis method was used to collect 4ml venous blood from 160 patients in 160 countries in 31 provinces (autonomous regions and municipalities) randomly from 1 to 59 years old in multiple stages. HBsAg and Anti- HBs. HBsAg-positive were further detected by HBeAg and Anti-HBe; 15 to 49-year-old women of childbearing age HBsAg and HBeAg epidemic situation analysis. Results After weight adjustment, the prevalence of HBsAg in Chinese women of childbearing age was 6.61% and the prevalence of Anti-HBs was 47.33%. Among HBsAg positive women of childbearing age, the prevalence of HBeAg was 23.51% and the prevalence of Anti-HBe was 75.54%. The prevalence of HBsAg in women of childbearing age was not significantly different among regions, towns and villages, ethnic groups and educational level. However, the prevalence of HBsAg in women of childbearing age in 20-24 and 30-34 years old was slightly higher than that of women of childbearing age Total HBsAg prevalence. Conclusions At the present stage of our country, the prevalence of HBsAg in women of childbearing age is 6.61%, slightly lower than the national average. 23.51% of HBsAg-positive women were HBsAg and HBeAg-positive.