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目的:探讨国产爱克赛尔药物洗脱支架、进口Cypher药物洗脱支架、金属裸支架治疗急性心肌梗死(AMI)或不稳定型心绞痛(UA)临床疗效的差异。方法:将126例在我院行PCI的冠心病患者分为三组,爱克赛尔药物洗脱支架组(65例),进口Cypher药物洗脱支架组(36例),金属裸支架组(25例),分析支架置入后6个月的支架内血栓发生率及6个月再狭窄率。结果:三组患者在术后血管通畅,心功能和住院期间心脏事件方面差异均无统计学意义,6～8个月后随访时,均无支架内血栓发生,国产爱克赛尔药物洗脱支架组的支架内再狭窄率为5.9%;进口Cypher药物洗脱支架组的支架内再狭窄率为3.7%;裸支架组的支架内再狭窄率为33.3%。结论:国产爱克赛尔药物洗脱支架、进口Cypher药物洗脱支架治疗AMI患者并未增加6个月内支架内血栓的发生,再狭窄率两者差异无统计学意义;与裸支架相比,两者6个月的再狭窄率显著降低。
OBJECTIVE: To investigate the clinical effects of domestic Ai-Qsail drug-eluting stent, imported Cypher drug-eluting stent and bare metal stent in the treatment of acute myocardial infarction (AMI) or unstable angina pectoris (UA). Methods: A total of 126 patients with coronary artery disease undergoing PCI in our hospital were divided into three groups. The patients in the group were divided into three groups: the drug elixir stent group (65 cases), Cypher drug eluting stent group (36 cases), the bare metal stent group 25 cases). The incidence of stent thrombosis and the rate of 6-month restenosis at 6 months after stenting were analyzed. Results: There was no significant difference in postoperative vascular patency, cardiac function and cardiac events during hospitalization. No stent thrombosis occurred after 6-8 months of follow-up. The domestic drug-eluting elution The rate of in-stent restenosis was 5.9% in the stent group and 3.7% in the Cypher drug-eluting stent group, and 33.3% in the bare stent group. Conclusion: Domestic patients with AMI and Cypher drug-eluting stent did not increase the incidence of stent thrombosis within 6 months. There was no significant difference in restenosis between the two groups. Compared with bare stent The restenosis rates of both groups were significantly lower at 6 months.