患女,28岁。无肝胆病史,初次妊娠,末次月经1981年3月25日。20周时全身皮肤出现搔痒,渐加重,两周后巩膜黄染,恶心。纳差、乏力。未服过避孕及其它致此症状药物,发病后未发现传染性。1981年入院时见:皮肤巩膜轻度黄染,皮肤布满抓痕。心肺正常,肝脾不大。有正常孕20周体征。黄疸指数10u,TTT正常, Female, 28 years old. No history of hepatobiliary disease, first pregnancy, the last menstrual March 25, 1981. Twenty weeks after the whole body itchy skin, gradually heavier, two weeks after the sclera yellow dye, nausea. Anorexia, fatigue. Did not take contraceptives and other symptoms of this drug, found no contagious. When admitted to hospital in 1981, see: skin scleral mild yellow dye, skin covered with scratches. Cardiopulmonary normal liver and spleen is not. There are signs of normal pregnancy 20 weeks. Jaundice index 10u, TTT normal,