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目的 探讨背向散射积分技术在评价糖尿病患者心肌病变方面的应用价值。方法 采用AgilentSonos550 0型超声诊断仪配置的声学密度定量分析软件 ,对比检测 60例Ⅱ型糖尿病患者 (I组 :无并发症者 30例 ;II组 :合并视网膜或肾脏等微血管病变者 30例 )和 30例健康志愿者不同节段心肌组织校正的背向散射积分均值 (IBS % )和背向散射积分周期变异率 (CVIB % )。结果 ①正常组心肌IBS %呈周期性变化 ,糖尿病各组IBS %亦呈周期性变化 ,但变化幅度减低 ;②糖尿病各组心肌IBS %均较对照组明显增高 ,糖尿病II组CVIB %较对照组显著减低 ;③左室收缩功能参数各组间无差异 ,舒张功能参数E峰和A峰的速度比值及时间速度积分比值糖尿病II组明显低于对照组 ,E峰减速时间明显高于对照组 ;④心肌IBS各参数与左室收缩和舒张功能参数之间未发现相关性 ,而室间隔与左室后壁的CVIB %与相应节段的室壁增厚率正相关。结论 糖尿病患者心肌组织背向散射积分参数与健康者显著不同 ,背向散射积分参数测定可以作为临床无创评价糖尿病患者心肌病变程度的方法
Objective To investigate the value of backscatter integration in the evaluation of myocardial lesions in diabetic patients. Methods Acoustic densitometry software was used to detect 60 patients with type 2 diabetes mellitus (group I: 30 patients without complications; group II: 30 patients with microvascular diseases such as retinal or renal) and The corrected backscatter integral mean (IBS%) and backscatter integral period mutation rate (CVIB%) were measured in different segments of myocardium in 30 healthy volunteers. Results ① The IBS% of the normal group showed a periodic change, the IBS% of the diabetic group also showed periodic changes, but the change range was lower. ② The myocardial IBS% of diabetic group was significantly higher than that of the control group. The CVIB% of diabetic group II was higher than that of the control group (3) There was no significant difference in LV systolic function parameters among all groups. The ratio of E and A peak diastolic velocity and the integral of time velocity in diastolic function group were significantly lower than those in control group, and the peak decelerating time of E peak was significantly higher than that in control group. ④ There was no correlation between myocardial IBS parameters and left ventricular systolic and diastolic function parameters, while CVIB% of ventricular septum and left ventricular posterior wall was positively correlated with ventricular wall thickening rate of corresponding segments. Conclusion The integral parameters of myocardial backscatter in diabetic patients are significantly different from those in healthy subjects. Backscatter integration parameters can be used as a noninvasive method to evaluate the degree of myocardial lesions in diabetic patients