3-脱氧-1,2:5,6-二-(O-异亚丙基)-α-D-赤-己-3-烯呋喃糖(Ⅰ)是合成某些氨基糖及其类似物和某些核苷等化合物的关键中间体。制备(Ⅰ)的方法以往文献中虽然已有报道,但各有一些缺陷,如关键步骤反应时间长、未能得到良好结晶、试剂昂贵,不宜用于较大量的制备。 Deoxy-1,2: 5,6-bis- (O-isopropylidene) -α-D-erythro-hex-3-enofuranose (I) is a method for the synthesis of certain amino sugars and their analogues and Some nucleosides and other compounds of the key intermediates. The preparation method of (I) has been reported in the literature in the past, but each has some drawbacks, such as long reaction time in the key step, failure to obtain good crystallization, expensive reagents and not suitable for larger quantities of preparation.