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目的:探讨洛伐他汀治疗高血脂症的疗效,为临床治疗提供参考。方法:58例高血脂症患者每晚餐后顿服洛伐他汀20mg,连续服用2个疗程后,观察临床疗效、服药前后血脂指标及不良反应。结果:58例病人对TC的有效率为88.89%(48/54),对LDL-C的有效率为88.89%(32/36),对TG的有效率为82.22%(37/45),对HDL-C的有效率为66.67%(20/30)。治疗前后TC,LDL-C,TG下降有显著性差异(p<0.05),HDL-C升高亦有统计学意义(p<0.05)。结论:洛伐他汀降脂疗效显著,价格低廉,是治疗高血脂症的理想药物之一。
Objective: To investigate the therapeutic effect of lovastatin on hyperlipidemia and provide reference for clinical treatment. Methods: 58 patients with hyperlipidemia were treated with lovastatin 20mg daily after meals, and after 2 courses of continuous treatment, the clinical curative effect, the blood lipid index and the adverse reactions before and after taking the medicine were observed. Results: The effective rate of TC was 88.89% (48/54) in 58 patients, 88.89% (32/36) in LDL-C, 82.22% (37/45) in TG, The effective rate of HDL-C was 66.67% (20/30). TC, LDL-C, TG decreased significantly before and after treatment (p <0.05), HDL-C increased also statistically significant (p <0.05). Conclusion: Lovastatin has significant effects on lipid lowering and is one of the ideal drugs for the treatment of hyperlipidemia.