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目的分析上皮样肉瘤样血管内皮细胞瘤(ES-H)的临床病理学特点及诊断要点。方法通过HE切片、免疫组化观察1例上皮样肉瘤样血管内皮细胞瘤,并结合文献讨论。结果主要病理学形态表现为瘤细胞呈实性片状或巢状分布,瘤细胞圆形或略呈梭形、多角形,胞质嗜酸性,胞质内可见空泡或血管腔形成。免疫组化示CK、vimentin、FLI-1和CD31均(+),而CD34和FⅧ(-)。结论 ES-H是一种罕见的肿瘤,生物学行为属于低度恶性,具有复发及远处转移的潜能,诊断需要依赖免疫组化,治疗及预后尚待观察。
Objective To analyze the clinicopathological features and diagnosis of epithelioid sarcomatoid hemangiopericytoma (ES-H). Methods One case of epithelioid sarcoma-like hemangioendothelioma was observed by HE section and immunohistochemistry, and the literature was discussed. Results The main pathological features of tumor cells were solid sheet or nevus. The tumor cells were round or slightly fusiform, polygonal, eosinophilic cytoplasm, vacuoles or blood vessel cavities were seen in cytoplasm. Immunohistochemistry showed CK, vimentin, both FLI-1 and CD31 (+), and CD34 and FⅧ (-). Conclusion ES-H is a rare tumor with low malignancy and potential for recurrence and distant metastasis. The diagnosis of ES-H depends on immunohistochemistry, treatment and prognosis.