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目的 观察口腔颌面部肿瘤患者T淋巴细胞核仁组成区相关蛋白 (Ag -NORs)的表达特点 ,以探讨其在口腔颌面部肿瘤诊断中的价值。方法 采用肿瘤免疫图像分析系统及配套试剂对正常人、口腔颌面部良、恶性肿瘤患者外周血T淋巴细胞Ag -NORs进行检测和分析。结果 正常人组与口腔颌面部良、恶性肿瘤组Ag-NORs值差异均有显著性 (P <0 0 1) ;同时 ,良、恶性肿瘤组Ag -NORs值差异仍有显著性 (P <0 0 1)。结论 外周血T淋巴细胞Ag -NORs表达与口腔颌面部肿瘤呈良好的相关性 ;Ag -NORs的检测值可作为口腔颌面部肿瘤诊断的重要参考指标
Objective To investigate the expression of Ag-NORs in oral and maxillofacial tumors and to explore its value in the diagnosis of oral and maxillofacial tumors. Methods Tumor immune image analysis system and its related reagents were used to detect and analyze the Ag-ORs of peripheral T lymphocytes in normal and oral and maxillofacial patients with benign and malignant tumors. Results There were significant differences in Ag-NORs between normal and oral and maxillofacial benign and malignant tumors (P <0.01). Meanwhile, the difference of Ag-NORs between benign and malignant tumors was still significant (P < 0 0 1). Conclusion The expression of Ag-NORs in peripheral blood T lymphocytes has a good correlation with oral and maxillofacial tumors. The detection value of Ag-NORs can be used as an important reference for the diagnosis of oral and maxillofacial tumors