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据估计,2000年全球新发癌症病例1010万,死亡620万;其中胃癌(gastric cancer,GC)新发病例为87.6万,约35%发生在我国;食管癌(esophagealcancer,EC)新发病例41.2万,我国食管癌发病数约占70%[1]。我国胃癌的年平均病死率约25.16/10万,居恶性肿瘤病死率的首位,食管癌的年平均死亡率为14.59/10万,居恶性肿瘤病死率的第3位[2]。江苏是全国胃癌和食管癌的高发省份之一,而位于苏中的扬州地区胃癌和食管癌也相对高发[3],其病因并不清楚。作者开展了以医院为基础的病例对照研究,以探索扬州地区胃癌、食管癌的危险因素,为针对性地开展胃癌、食管癌的防治措施提供科学依据。
It is estimated that there were 10.1 million new cancer cases in the world in 2000 with a death toll of 6.2 million. Among them, 876,000 new cases of gastric cancer (GC) occurred in about 35% of cases in our country; 41.2 new cases of esophageal cancer (EC) Million, the incidence of esophageal cancer accounts for about 70% [1]. The annual average mortality rate of gastric cancer in China is 25.16 / 100000, ranking the first place in the mortality rate of malignant tumors. The annual average death rate of esophageal cancer is 14.59 / 100000, which ranks the third in malignant tumor mortality [2]. Jiangsu is one of the high incidence provinces for gastric and esophageal cancers in the country. The gastric and esophageal cancers in Yangzhou, located in central Jiangsu Province, are also relatively high [3]. The etiology of the disease is not clear. The authors conducted a hospital-based case-control study to explore the risk factors of gastric cancer and esophageal cancer in Yangzhou and provide scientific evidence for targeted prevention and treatment of gastric cancer and esophageal cancer.