检测了６２例卵巢癌患者血清中白细胞介素６（Ｉｎｔｅｒｌｅｕｋｉｎ－６，ＩＬ－６）的水平，并对卵巢癌患者术前和术后血清中ＩＬ－６水平进行了研究。结果发现：卵巢癌组血清ＩＬ－６值为（１６５６±２５７１）ｐｇ／ｍｌ，明显高于正常对照组（１６４±１３２）ｐｇ／ｍｌ和卵巢囊肿组（５５８±２８４）ｐｇ／ｍｌ，且卵巢癌患者术前血清中ＩＬ－６（１４４８±１９７６）ｐｇ／ｍｌ明显高于术后（５９８±１７３）ｐｇ／ｍｌ。另外发现９例卵巢患者腹水中ＩＬ－６活性为（７５９３±３２３１）ｐｇ／ｍｌ，明显高于血清。结果表明：检测ＩＬ－６可以作为卵巢癌诊断的标记物之一，以及对治疗和判断预后具有重要的价值。 The levels of serum interleukin-6 (IL-6) in 62 patients with ovarian cancer were detected. The levels of IL-6 in preoperative and postoperative serum of ovarian cancer patients were also studied. The results showed that the serum level of IL-6 in ovarian cancer group was (165.6 ± 257.1) pg / ml, which was significantly higher than that in normal control group (16.4 ± 13.2) pg / ml and ovarian cyst group 8 ± 284) pg / ml, and IL-6 (1448 ± 1976) pg / ml in preoperative serum of patients with ovarian cancer was significantly higher than that of postoperative (598 ± 173) pg / ml . In addition, the activity of IL-6 in ascites was found to be (759.3 ± 323.1) pg / ml in 9 cases of ovarian patients, which was significantly higher than that of serum. The results showed that the detection of IL-6 could be one of the markers for the diagnosis of ovarian cancer and has important value in the treatment and prognosis.