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3—氯丙烯(Allyl Chloride,3-Chloropene-1)为不饱和脂肪族氯代烃类化合物,常态下是无色透明有辛辣味易于挥发的液体。工业中除用以生产环氯丙烷、环氧树脂、合成甘油外,还用以制备丙烯磺酸钠,是聚丙烯晴纤维生产中的重要原料。国外资料认为氯丙烯属于亲肝毒物,但国内发现本品慢性中毒主要损害周围神经。我们自1973年起在某厂丙烯磺酸钠生产车间接触氯丙烯的工人中,陆续观察到中毒性多发性神经病的病例。现将有关临床研究资料总结如下,供防治工作的参考。
Allyl Chloride (3-Chloropene-1) is an unsaturated aliphatic chlorinated hydrocarbon compound. Normally it is a colorless and transparent liquid that is spicy and easy to volatilize. In addition to the industrial production of cyclopropane chloride, epoxy resin, synthetic glycerin, but also for the preparation of sodium propylene sulfonate, polypropylene fiber is an important raw material in the production of clear fiber. Foreign information that allyl chloride belongs to the pro-liver poison, but this product is mainly found in chronic poisoning peripheral nerves. We have successively observed cases of toxic polyneuropathy in workers exposed to allyl chloride in the sodium propionate sodium plant in a factory since 1973. Now the clinical research data are summarized below, for the prevention and treatment work reference.