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目的探讨糖尿病性视网膜病变(DR)发生发展的相关因素及中西医结合疗法的临床疗效。方法选取2013年1月—2015年1月汉中市中心医院收治的DR患者50例作为DR组,随机分为观察组与对照组,各25例;另选取同期单纯糖尿病(DM)患者50例作为无DR组。观察组患者予以中西医结合疗法治疗,对照组患者予以西医疗法治疗。观察所有患者视力改善情况、眼底病改善情况变情况及中医证候改善情况。结果年龄、病程、高低密度脂蛋白胆固醇(LDL-C)、高血压、高尿酸、冠心病、肾病、周围神经病变均为DR的影响因素(P<0.05);年龄、病程、高LDL-C、高血压、高尿酸、冠心病、肾病、周围神经病变均为DR的危险因素;观察组患者视力改善总有效率、眼底病变改善总有效率、中医证候改善总有效率高于对照组,差异有统计学意义(P<0.05)。结论病程、高LDL-C、高血压、高尿酸、冠心病、肾病、周围神经病变是DR的危险因素,中西医结合疗法治疗DR的临床疗效显著,可提高患者视力,改善眼底病变及临床症状。
Objective To investigate the related factors of the development of diabetic retinopathy (DR) and the clinical efficacy of integrated traditional Chinese and western medicine. Methods 50 patients with DR in our hospital from January 2013 to January 2015 in Hanzhong Central Hospital were randomly divided into observation group (n = 25) and control group (n = 25). 50 patients with simple diabetes mellitus (DM) No DR group. Patients in the observation group were treated with Integrative Medicine, and patients in the control group were treated with Western medicine. Observed in all patients with visual acuity improvement, fundaciosis to improve the situation and the improvement of TCM syndromes. Results The age, course of disease, high and low density lipoprotein cholesterol (LDL-C), hypertension, hyperuricemia, coronary heart disease, nephropathy and peripheral neuropathy were the influential factors of DR (P <0.05) C, hypertension, hyperuricemia, coronary heart disease, nephropathy and peripheral neuropathy were all risk factors of DR. The total effective rate of visual acuity improvement and total effective rate of fundus lesion in the observation group were higher than those in the control group , The difference was statistically significant (P <0.05). Conclusion The course of disease, high LDL-C, hypertension, hyperuricemia, coronary heart disease, nephropathy and peripheral neuropathy are the risk factors of DR. The clinical curative effect of traditional Chinese medicine and western medicine in treating DR is significant, which can improve the visual acuity, improve the retinopathy and clinical symptoms .