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用回顾性队列研究方法对接触CO的1708名工人在1971～1985年的死亡情况进行分析,用当地居民及不接触毒物的轧钢厂工人做对照。结果表明,工作现场历年CO浓度平均值超标比较严重。与对照比较,全癌亡、肝癌亡的SMR值差别高度显著;胃癌亡、肺癌亡的SMR值差别显著。全癌亡高峰比当地居民提前10岁。接触CO30年以后全癌亡人数增加明显。全癌亡随年代呈上升趋势。50年代以前参加工作的工人或25岁以前参加工作的工人全癌亡率较高。粗线条反映出接触CO与恶性肿瘤死亡的剂量反应关系。
A retrospective cohort study was conducted to analyze the deaths of 1,708 workers exposed to CO between 1971 and 1985 using controls for locals and workers who did not contact with the rolling mill. The results show that over the past years, the average concentration of CO over the past years is more serious. Compared with the control group, the difference of SMR between total cancer death and liver cancer death was highly significant. The difference of SMR between gastric cancer death and lung cancer death was significant. All cancer death peak than the local residents 10 years of age. After 30 years of contact with CO, their numbers have increased. Total cancer deaths with the age is on the rise. Workers who participated in the work before the 1950s or those who joined the work before the age of 25 had higher rates of total cancer. Thick lines reflect the dose-response relationship between exposure to CO and malignant tumor death.