论文部分内容阅读
目的探讨超选择性动脉插管持续灌注化疗对妇科恶性肿瘤的应用价值和效果。材料和方法对47例晚期妇科恶性肿瘤进行了超选择动脉持续灌注化疗，其中36例宫颈癌（Ⅱb－Ⅳ期），6例卵巢癌（Ⅲ期一Ⅳ期），5例子宫内膜癌（Ⅲ期）。平均年龄52岁，采用经皮穿刺股动脉置管于患侧骼内动脉之肿瘤供血动脉内、连接蠕动式动脉输液泵、进行持续性两天大剂量化疗药物灌注治疗。结果47例中完全缓解1例，部分缓解44例，稳定2例，总有效率95％，5例局部臂部皮肤发生缺血后改变占1％。结论超选择性动脉插管持续性灌注化疗对妇科恶性肿瘤的治疗是一种有效的治疗手段，不但能控制和治疗晚期肿瘤，同时可能为不能手术病人提供了再次手术切除的机会。
Objective To investigate the application value and effect of superselective arterial continuous infusion chemotherapy for gynecological malignancies. Materials and Methods Superselective arterial continuous infusion chemotherapy was performed on 47 cases of advanced gynecologic malignancies, including 36 cases of cervical cancer (stage IIb-IV), 6 cases of ovarian cancer (stage III-IV), and 5 cases of endometrial cancer ( Phase III). The average age was 52 years. Percutaneous transfemoral femoral artery was placed in the tumor supplying arteries of the ipsilateral internal iliac artery, connected to a peristaltic arterial infusion pump, and subjected to continuous high-dose chemotherapy for two days. Results In 47 cases, 1 case was complete remission, 44 cases were partial remission, 2 cases were stable, and the total effective rate was 95%. 5 cases of local arm skin changes after ischaemia accounted for 1%. Conclusions Continuous infusion of superselective arterial infusion chemotherapy is an effective treatment for the treatment of gynecological malignancies. It can not only control and treat advanced tumors, but also provide an opportunity for reoperation for inoperable patients.