口腔变形链球菌 S.mutans 所产生的非水溶性多糖——α(1,3)糖苷键变聚糖(mut-an),是龋齿形成的关键因素之一。这种非水溶性多糖的粘附力强,不能被一般的葡聚糖酶所降解。它们粘附到牙齿表面,作为“基地”聚集口腔微生物成为牙菌斑,牙菌斑上的微生物分解糖类产酸,长期局部产酸导致牙釉质脱钙,进一步发展便有可能形成龋齿。如果能找到一种可降解该多糖的酶,便有可能 One of the key factors in dental caries formation is the non-water-soluble polysaccharide - α (1,3) glucosidase produced by Streptococcus mutans S.mutans. This water-insoluble polysaccharide has strong adhesion and can not be degraded by normal glucanase. They adhere to the surface of the tooth as a “base” to accumulate oral microbes to become plaque, where the microorganisms on the plaque decompose sugars to produce acid, long-term local acid production causes decalcification of the enamel, and further development may result in the formation of dental caries. If you can find an enzyme that can degrade the polysaccharide, it is possible