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目的研究以碘油为主组合不同栓塞剂型治疗子宫肌瘤的疗效。方法36例子宫肌瘤患者,随机分为3组,采用与碘油不同栓塞剂组合,行双侧子宫动脉栓塞(UAE)治疗。Ⅰ组碘油+无水乙醇;Ⅱ组碘油+平阳霉素;Ⅲ组碘油+平阳霉素+无水乙醇+明胶海绵粒。术后随访观察月经恢复情况、瘤体大小、有无并发症发生等。结果Ⅰ、Ⅱ、Ⅲ3组UAE治疗后,子宫肌瘤缩小>50%分别为3、4、8例,Ⅰ、Ⅱ组间无显著性差异(P>0.05);Ⅰ、Ⅱ组与Ⅲ3组之间有显著性差异(P<0.05);Ⅰ、Ⅱ、Ⅲ3组间并发症发生率无统计学差异(P>0.05)。结论碘油与无水乙醇、平阳霉素、明胶海绵粒联合栓塞子宫肌瘤其疗效优于其它组合剂型。
Objective To study the efficacy of different embolic dosage forms based on lipiodol in the treatment of uterine fibroids. Methods Thirty - six patients with uterine leiomyomas were randomly divided into three groups. The patients were treated with different embolization agents of lipiodol and treated with UAE. Group I lipiodol + ethanol; Group II lipiodol + pingyangmycin; Group III lipiodol + pingyangmycin + ethanol + gelatin sponge. Postoperative follow-up observation of menstruation, tumor size, with or without complications. Results After UAE treatment in group Ⅰ, Ⅱ and Ⅲ3, the uterine fibroids were reduced by> 50% in 3, 4 and 8 cases respectively. There was no significant difference between Ⅰ and Ⅱ (P> 0.05) There was a significant difference between the two groups (P <0.05). There was no significant difference in the incidence of complications among Ⅰ, Ⅱ and Ⅲ groups (P> 0.05). Conclusion Lipiodol and ethanol, Pingyangmycin, gelatin sponge embolization of uterine fibroids superior to other combination formulations.