论文部分内容阅读
将DPN 76例患者随机分成两组。A组:α-硫辛酸联合甲钴胺、依帕司他,B组:甲钴胺联合依帕司他,连续治疗三周。比较两组治疗前后症状、体征和神经传导速度。结果两组患者的神经症状和体征及神经传导功能都得到明显改善,其应用α-硫辛酸联合甲钴胺、依帕司他治疗组可以更加明显改善DPN患者症状及体征,更明显增加神经病变组织的传导速度,疗效显著。结论运用α-硫辛酸联合甲钴胺、依帕司他治疗糖尿病周围神经病变,可显著提高临床疗效,改善患者的生活质量。
76 patients with DPN were randomly divided into two groups. Group A: α-lipoic acid combined with mecobalamin, epalrestat, B group: mecobalamin combined with epalrestat, continuous treatment for three weeks. The symptoms, signs and nerve conduction velocity before and after treatment were compared between the two groups. Results The neurological symptoms and signs and nerve conduction function of both groups were significantly improved. The application of α-lipoic acid combined with mecobalamin and epalrestat could obviously improve the symptoms and signs of patients with DPN, and more obviously increase the neuropathy Tissue conduction velocity, significant effect. Conclusions The use of α-lipoic acid combined with mecobalamin and epalrestat in the treatment of diabetic peripheral neuropathy can significantly improve the clinical efficacy and improve the quality of life of patients.