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尿毒症贫血慢性肾功衰竭发展到尿毒症时,常伴有骨髓红细胞生成障碍,因而贫血或轻或重必然发生。且其程度随氮质血症的发展而加重。Kaye报告血尿素氮每升高8毫克%,则血红蛋白降低1克%,血红蛋白降低和尿素氮升高呈直线相关。Kasanen等分析了266例慢性肾小球肾炎尿毒症患者肌酐清除率<10毫升/分,P.S.P.排泄<20%/2小时,N.P.N.>70毫克%者均有贫血。尿毒症贫血除非伴有铁的缺乏(失血、吸收不良、摄入减少等),一般为正常细胞、正常血色素性贫血。外周血及骨髓形态学多示正
Uremia Anemia Chronic renal failure develops into uremia, often accompanied by bone marrow erythropoietic disorders, thus anemia or light or heavy must happen. And the extent of aggravating the development of azotemia. Kaye reported that for each 8 mg / kg increase in blood urea nitrogen, hemoglobin decreased by 1% and hemoglobin decreased in a linear relationship with elevated urea nitrogen. Kasanen et al. Analyzed the creatinine clearance rate of <10 mL / min for uremic patients with chronic glomerulonephritis and anemia for those with P.S.P. excretion <20% / 2 h and N.P.N.> 70 mg%. Uremic anemia unless accompanied by a lack of iron (blood loss, malabsorption, reduced intake, etc.), usually normal cells, normal hemochromatosis anemia. Peripheral blood and bone marrow morphology more positive