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本文复习了卵巢癌病人单次应用和长期腹腔内导管给予顺氯氨铂行腹腔内化疗的经验。研究包括28例卵巢癌病人,在细胞减数术加全身化疗后给予腹腔内(ip)顺氯氨铂化疗。除1例外均行腹腔镜和/或二次剖腹探查术,并证实有较少的残余上皮性卵巢癌;另1例病人经CT扫描证实。病人ip化疗用单次或长期导管给予顺氯氨铂。长期导管在全麻或局麻下直视插入,单次导管在局麻下盲目经皮插入。导管插入后以重力向腹腔内输入21室温等渗盐水,然后给予顺氯氨铂。长期导管保留7~10天进行化疗,单次导管用后即拨除,下次化疗重新插入。 28例病人中12例次置长期导管,21例次置单次
This article reviews the experience of single-use ovarian cancer patients and long-term intraperitoneal catheter cisplatin given intraperitoneal chemotherapy. The study included 28 patients with ovarian cancer who underwent intraperitoneal (ip) cisplatin chemotherapy after cytoreductive surgery plus systemic chemotherapy. Laparoscopy and / or secondary laparotomy were performed with 1 exception, and less residual epithelial ovarian cancer was confirmed. One patient was confirmed by CT scan. Patient chemotherapy with cisplatin single or long-term catheter cisplatin. Long-term catheter insertion under general anesthesia or local anesthesia, a single catheter under local anesthesia blind percutaneous insertion. Catheterization was performed by intraperitoneal infusion of 21 room temperature isotonic saline by gravity followed by cisplatin. Long-term catheter to retain 7 to 10 days for chemotherapy, after a single catheter is removed, the next chemotherapy reinserted. Of the 28 patients, 12 patients underwent long-term catheterization and 21 were single-ended times