论文部分内容阅读
给BALB/C系小鼠经口染毒铅或锌的无离子水溶液16周后,测定了小鼠末梢血红细胞σ-氨基酮戊酸脱水酶(σ-ALAD)活性和脾脏淋巴细胞对植物血凝索和刀豆素刺激的增殖反应。结果表明,铅接触组的未梢血红细胞σ-ALAD活性和脾脏植物血凝素和刀豆素所致T淋巴细胞增殖反应明显地低于对照组(P<0.05),而15.2mmol/L锌能拮抗2.4mmol/L铅抑制σ-ALAD活性和脾脏刀豆素所致T淋巴细胞增殖反应。
After 16 weeks of oral exposure to a solution of lead or zinc in an ion-free aqueous solution of BALB/C mice, the activity of σ-aminolevulinic acid dehydratase (σ-ALAD) and spleen lymphocyte to vegetative blood of mouse peripheral red blood cells were measured. Coagulation and concanavalin-stimulated proliferative responses. The results showed that the activity of σ-ALAD in peripheral blood red blood cells in the lead exposure group and the T cell proliferation induced by hemagglutinin and concanavalin in the spleen were significantly lower than those in the control group (P<0.05), while zinc was 15.2 mmol/L. It can antagonize 2.4 mmol/L lead to inhibit σ-ALAD activity and spleen concanamin-induced T lymphocyte proliferative response.