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目的:研究痰热清联合阿奇霉素治疗急性小儿支原体肺炎的临床疗效和安全性。方法:将80例确诊为急性支原体肺炎的患儿随机分为观察组和对照组,各40例。对照组采用以阿奇霉素为主的抗感染治疗方案进行治疗,观察组联合应用痰热清进行辅助治疗,比较两组治疗效果。结果:观察组患儿退热时间、肺部啰音消失时间、胸片恢复正常时间、MP-IgM转阴时间均明显提前,观察组治疗效果优于对照组,组间差异具有统计学意义(P<0.05)。结论:痰热清联合阿奇霉素治疗小儿急性支原体肺炎安全有效,值得临床进一步研究应用。
Objective: To study the clinical efficacy and safety of Tanreqing combined with azithromycin in the treatment of acute mycoplasma pneumonia in children. Methods: Eighty children diagnosed with acute mycoplasmal pneumonia were randomly divided into observation group and control group, 40 cases each. The control group was treated with azithromycin-based anti-infective therapy. The observation group was treated with Tanreqing for adjuvant therapy. The therapeutic effect was compared between the two groups. Results: In the observation group, the antipyretic time, the disappearance of pulmonary rales, the time of recovery of the chest radiograph and the time of MP-IgM negative conversion were both significantly earlier than those of the control group, and the difference between the two groups was statistically significant ( P <0.05). Conclusion: Tanreqing combined with azithromycin in children with acute mycoplasma pneumonia is safe and effective, it is worth further clinical study.