为了证明关节活动受限与早发微血管病变间的关系,作者观察了309例糖尿病(年龄1～2.8岁)病人的临床经过,发现92例关节活动受限。受限程度分为(1)轻度:1或2个指(趾)间关节受累,1大关节或双侧掌指关节受累;(2)中度:3个或更多指(趾)间关节受累或1指关节和1大关节双侧受累; To demonstrate the relationship between limited joint activity and premature microangiopathy, we examined the clinical course of 309 patients with diabetes mellitus (ages 1 to 2.8 years) and found 92 patients with restricted joint activity. Restrictions are categorized as (1) Mild: 1 or 2 metacarpophalangeal involvement, 1 major or bilateral metacarpophalangeal involvement; (2) Moderate: 3 or more digits Joint involvement or 1 knuckles and 1 major joint bilateral involvement;