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目的探讨高敏C反应蛋白(hs-CRP)在2型糖尿病(T2DM)血管性病变中的作用及临床价值。方法96例T2DM患者分为有血管性病变组(50例)和无血管性病变组(46例),正常健康者50例为对照组,采用透射比浊法分别测定hs-CRP浓度,常规检测血脂水平。结果有血管性病变组与无血管性病变组hs-CRP水平较对照组明显增高(P<0.05),且有血管性病变组hs-CRP水平显著高于无血管性病变组(P<0.05);TC、LDL-C和HDL-C水平组内组间比较差异均无统计学意义(P>0.05)。结论hs-CRP可作为T2DM血管性病变诊断的重要指标,具有重要的临床价值。
Objective To investigate the role and clinical value of high-sensitivity C-reactive protein (hs-CRP) in vascular lesions of type 2 diabetes mellitus (T2DM). Methods 96 patients with T2DM were divided into vascular lesion group (50 cases) and non-vascular lesion group (46 cases), and normal healthy 50 cases as control group. The hs-CRP concentrations were determined by transmission turbidimetry. Lipid levels. Results The hs-CRP levels in patients with vascular disease and without vascular disease were significantly higher than those in control group (P <0.05), and the levels of hs-CRP in patients with vascular disease were significantly higher than those without vascular disease (P <0.05) There were no significant differences among the groups of TC, LDL-C and HDL-C (P> 0.05). Conclusion hs-CRP can be used as an important index in the diagnosis of T2DM vascular lesions, and has important clinical value.