本文报道了用中医中药理论,结合现代药理学、制剂学研制纯中药制剂牙神液的方法及结果。牙神液为一种治疗因口腔疾病引起的疼痛及炎症的含漱剂。经一系列药敏学、毒理学动物试验及107例临床观察,证明本品具有显著的消肿、止痛功效,总有效率为95.33％。与对照组牙痛水比较,经统计学处理,X~2=17.2,P<0.01,有显著性差异;且未发现任何不良反应、毒副作用及禁忌症。 This article reports on the method and results of the development of a pure traditional Chinese medicine preparation, Teijin Liquid, using traditional Chinese medicine theory, combined with modern pharmacology and formulation. Toothpaste is a tincture for the treatment of pain and inflammation caused by oral diseases. After a series of susceptibility, toxicology animal experiments and 107 clinical observations, this product proved to have significant swelling, analgesic efficacy, the total effective rate was 95.33%. Compared with the control group toothache water, statistically, X~2=17.2, P<0.01, there was a significant difference; and no adverse reactions, toxic side effects and contraindications were found.