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目的探讨前列腺炎患者血清中免疫球蛋白水平与症状评分及治疗效果的关系。方法选择2014年7月-2015年7月在本院诊断为前列腺炎的患者60例,检测患者血清中IgA、IgG、IgM水平,采用慢性前列腺炎症状指数(NIH-CPSI)来探讨前列腺炎患者症状严重程度,对比治疗效果不同患者血清中免球蛋白水平,并探讨IgA、IgG、IgM与患者前列腺症状评分的关系。结果IgA、IgG、IgM高水平组患者疼痛评分、排尿评分、生活质量评分和CPSI总评分高于IgA、IgG、IgM低水平组患者,差异有统计学意义(P<0.05)。60例患者中显效17例,有效29例,无效14例,显效患者IgA、IgG、IgM水平高于有效、无效患者,且组间差异有统计学意义(P<0.05)。IgA、IgM、IgG水平与疼痛评分、排尿评分、生活质量评分、CPSI总评分及治疗效果均呈正相关(P<0.05)。结论前列腺炎患者血清免疫球蛋白水平与患者症状及治疗效果呈正相关。
Objective To investigate the relationship between serum immunoglobulin levels and symptom scores and therapeutic effect in patients with prostatitis. Methods Sixty patients diagnosed as prostatitis in our hospital from July 2014 to July 2015 were enrolled in this study. Serum levels of IgA, IgG and IgM were measured in patients with prostatitis, and chronic prostatitis symptom index (NIH-CPSI) The severity of symptoms was compared with that of patients with different therapeutic effects, and the relationship between IgA, IgG, IgM and the score of prostate symptoms was also discussed. Results The scores of pain, voiding, quality of life and total CPSI in patients with IgA, IgG and IgM were significantly higher than those in patients with low IgA, IgG and IgM (P <0.05). Among the 60 patients, 17 cases were markedly effective, 29 cases were effective and 14 cases were ineffective. The levels of IgA, IgG and IgM were significantly higher in effective patients than those in effective and ineffective patients. The difference was statistically significant (P <0.05). IgA, IgM and IgG levels were positively correlated with pain score, urination score, quality of life score, total CPSI score and therapeutic effect (P <0.05). Conclusion Serum immunoglobulin levels in patients with prostatitis are positively correlated with the symptoms and the treatment effect.