放射主要作用于细胞核DNA,也可作用于细胞膜或细胞浆而启动一些信号传导路径,调整细胞的放射反应,导致细胞内和(或)细胞间传导信号网络的改变,使肿瘤细胞或阻滞在某一细胞周期启动DNA放射损伤修复或死亡。从图1可看出细胞放射生物效应不仅和DNA直接损伤相关,而且也和放射损伤胞 Radiation plays a major role in nuclear DNA, but also acts on the cell membrane or cytoplasm to initiate some signaling pathways that regulate the radioresistance of cells, resulting in changes in the network of signaling signals within and / or between cells, causing tumor cells or arrest in A certain cell cycle initiates DNA damage repair or death. It can be seen from Figure 1 that the radiobiological effects of cells are not only associated with direct DNA damage, but also with radiation-injured cells