血液透析是终末期肾功能衰竭患者的替代疗法之一,在临床上广泛应用。然而长期的血液透析给患者带来不少的并发症(如低血压、肌肉痉挛、心律失常等)使患者的生活质量降低。其原因可能与体内肉碱缺乏有关。肉碱的主要生理功能是将长链脂肪酸从细胞浆转运到线粒体内,进行β氧化供能,产生三磷酸腺苷,外源性补充左旋肉碱(左卡尼汀)可改善慢性肾衰血液透析患者的肉碱缺乏症,使并 Hemodialysis is one of the alternative therapies in patients with end-stage renal failure, widely used clinically. However, long-term hemodialysis patients to bring a lot of complications (such as hypotension, muscle spasms, arrhythmias, etc.) to reduce the quality of life of patients. The reason may be related to the lack of carnitine in vivo. The main physiological function of carnitine is the long-chain fatty acids transported from the cytoplasm to the mitochondria for β oxidation for energy, produce adenosine triphosphate, exogenous supplementation of L-carnitine (levocarnitine) can improve chronic renal failure hemodialysis patients Carnitine deficiency, so and