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本实验观察表明,阻断犬冠脉血流后,血小板聚集率、左室舒张末期压和左室等容舒张末期压力下降时间常数增加,左室内压最大下降速率和左室肌收缩成分舒张速度降低。缺血边缘区心肌舒张末期节段长度延长,室壁厚度、长度缩短变化百分率和室壁厚度变化百分率均减小。静脉输注阿司匹林精氨酸抑制血小板聚集功能后阻断冠脉,上述反映上室肌舒张功能的各参数变化程度均减轻。
The experimental observation showed that blocking canine coronary blood flow, platelet aggregation rate, left ventricular end-diastolic pressure and left ventricular end-diastolic pressure drop time constant increased, the maximum rate of decline in left ventricular pressure and left ventricular systolic component diastolic velocity reduce. The length of myocardial end-diastolic segment of ischemic border area was prolonged, the percentage of change of wall thickness, shortening of length and percent change of wall thickness were all decreased. Intravenous aspirin arginine inhibition of platelet aggregation after blocking the coronary artery, the above parameters reflect the relaxation of the upper compartment of the degree of change are reduced.