豚鼠钩端螺旋体病肺弥漫性出血实验模型肝、肾、心等组织的电镜观察,揭示了这些器官和组织之中含有较多的钩端螺旋体,特别是分布在细胞外、组织间隙中。而在细胞中则较为少见,因而早期采用有效的抗菌素,阻断钩端螺旋体毒素对各器官的损伤,以期减少或者完全避免后期肝、肾、心等发生病变和避免肺大出血的发生。 Electron microscopic observation of the liver, kidney, heart and other tissues in experimental models of leptospirosis of guinea pig revealed that these organs and tissues contain more Leptospira, especially in the extracellular and interstitial spaces. While in cells is relatively rare, so the early use of effective antibiotics, blocking Leptospira toxin damage to various organs in order to reduce or completely avoid late liver, kidney, heart lesions and avoid the occurrence of pulmonary hemorrhage.