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老年性白内障 79例 ,随机分成两组 ,行超声乳化摘除联合人工晶体植入术。对照组灌注液为平衡盐液 ,实验组中灌注液为平衡盐液中加入肝素 5 0 IU/ ml,观察对后囊混浊的影响。结果术后 1年纤维化型后囊混浊明显减少 ,说明肝素在一定程度上抑制后囊混浊的发生。作用机制可能是抗炎、抑制晶体上皮细胞生长和溶解纤维蛋白等。肝素组 2例前房少量积血 ,常规治疗 3天内吸收 ,角膜反应与对照组相同 ,提示肝素应用安全
79 cases of senile cataract, were randomly divided into two groups, phacoemulsification combined with intraocular lens implantation. In the control group, the perfusion fluid was balanced salt solution. In the experimental group, the perfusion fluid in the experimental group was added heparin (50 IU / ml) to observe the effect on the posterior capsule opacity. Results One year after operation, fibrosis-type posterior capsule opacification decreased significantly, indicating that heparin inhibited the occurrence of posterior capsule opacification to a certain extent. Mechanism of action may be anti-inflammatory, inhibit the growth of epithelial cells and dissolve fibrin and so on. Heparin group, 2 cases of anterior chamber hemorrhage, routine treatment within 3 days of absorption, corneal reaction with the same control group, suggesting that heparin safety