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目的:探讨我院药品不良反应(ADR)报告的特点,为临床安全用药提供参考。方法:对我院2010年1～4月346例ADR报告进行分类统计、分析。结果:346例ADR涉及药品17类136种,以抗微生物类药引发ADR例数最多(32种,103例),其次是营养药、中药制剂、抗肿瘤类药;给药途径以静滴为主,多为单一用药方式;ADR累及的器官或系统,以消化系统损害最多(31.21%),其次是皮肤及其附件损害(20.8%);346例ADR中新的一般的ADR40例,严重ADR 1例。结论:应重视ADR的监测和上报工作,规范临床合理用药,减少或避免ADR发生。
Objective: To investigate the characteristics of adverse drug reaction (ADR) reports in our hospital and provide references for clinical safety medication. Methods: A total of 346 cases of ADR from January to April in our hospital were classified and analyzed. RESULTS: 346 cases of ADR involved 136 kinds of drugs in 17 categories, with the highest number of anti-microbial agents (32 cases, 103 cases), followed by nutritional drugs, traditional Chinese medicine preparations and anti-tumor drugs; ADR involved organ or system with the most damage to the digestive system (31.21%), followed by damage to the skin and its accessory (20.8%); the new general ADR was found in 346 cases of ADR with severe ADR 1 case. Conclusion: We should pay attention to the monitoring and reporting of ADR, standardize the clinical rational use of drugs, reduce or avoid the occurrence of ADR.