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胃粘膜内异型性腺体囊性扩张(简称异型囊),在文献中报告较少,现对其在胃粘膜活检中检出的意义作初步探讨。病例 男性,70岁,胃镜号:89—19037。因纳差伴黑便20天,当地医院疑诊上消化道出血,经止血、补液、保护胃粘膜等治疗一周后血止,大便转黄,行上消化道钡餐检查未见异常。来我院作胃镜检查,见胃粘膜红白相间,窦部有散在性红色结节,并有少许粘液斑,蠕动尚可;活俭病理检查示:胃窦部粘液细胞癌,其旁粘膜见多个腺管异型囊性扩张伴肠腺化生,住院手术切除,病理报告证实为粘液细胞癌,早期阶段。讨论 根据胃粘膜腺体扩张的病理形态,可分为单纯扩张和异型扩张。单纯扩张腺体扩张轻微,为局灶性或孤立性,腺体内粘液分泌增多,腺体多无萎缩,腺上皮亦无异型性;异型扩张,腺体扩张普遍而严重,粘液分泌多减少,腺体萎缩,腺上皮异型增生,并可伴有
Abnormal cystic dilatation in the gastric mucosa (abbreviated as heterotypic sac) has been reported in the literature. The significance of its detection in gastric biopsy is discussed. Cases Male, 70 years old, gastroscope number: 89-19037. Due to the difference in nausea with melena for 20 days, local hospitals suspected of upper gastrointestinal hemorrhage, bleeding, rehydration, and protection of the gastric mucosa after a week of treatment, the blood stopped, the stool turned yellow, and no abnormalities were observed in the upper digestive tract barium meal examination. To our hospital for gastroscopy, see the red and white gastric mucosa, sinus with scattered red nodules, and a little sticky spots, peristalsis can be; live phlegm pathological examination showed: antral mucinous cell carcinoma, its adjacent mucosa see Multiple glandular cystic dilatation with intestinal metaplasia, hospitalization resection, pathological reports confirmed mucinous cell carcinoma, early stage. Discussion According to the pathological morphology of the glandular expansion of the gastric mucosa, it can be divided into simple expansion and heterotypic expansion. Slight expansion of the gland to dilate slightly, as focal or solitary, gland mucus secretion increased, there is no more atrophy of glands, glandular epithelium also no abnormality; heterogeneous expansion, gland expansion is widespread and serious, mucus secretion decreased, Glandular atrophy, glandular epithelial dysplasia, and may be accompanied