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通过对不同原因两组肌病的临床及肌电图(EMG)等研究,对其诊断和鉴别诊断提供帮助。方法18例脂质沉积性肌病(简称第1组)和18例炎性肌病(简称第2组)均行常规同心圆针电极EMG检查;肌肉病理检查包括各种组织化学染色的光镜检查和常规超薄切片的电镜检查。结果第1组EMG自发电位为14%明显低于第2组的55%(P<0.001);其他各项EMG参数两组之间差异无显著意义;有肌痛者,自发电位检出率在第1组占22%,第2组占70%,明显高于第1组(P<0.001)。结论通过两组肌病的对比,如临床上有明显的肌肉无力和疼痛、血肌酶谱升高、在疼痛部位未找到或偶见自发电位者,应考虑脂质沉积性肌病的可能。
Through the two different causes of myopathy and clinical EMG (EMG) and other research, its diagnosis and differential diagnosis to help. Methods 18 cases of lipid deposition myopathy (referred to as the first group) and 18 cases of inflammatory myopathy (referred to as the second group) were performed concentric needle electrode EMG examination; muscle pathology including various histochemical staining light microscopy Check and conventional ultra-thin sections of the electron microscopy. Results The spontaneous potential of EMG in group 1 was significantly lower than that in group 2 (14% vs 55%, P <0.001). There were no significant differences in the other EMG parameters between the two groups. Rates were 22% in group 1 and 70% in group 2, significantly higher than group 1 (p <0.001). Conclusion The comparison of the two groups of myopathy, such as clinically significant muscle weakness and pain, increased serum creatinine, not found in the pain or occasionally spontaneous potentials should consider the possibility of lipid deposition myopathy.