论文部分内容阅读
本文通过脑内慢性埋植套管向家兔一侧隔区或伏核内注射微量(10 nmol)CaCl_2或MgCl_2,可显著对抗吗啡镇痛和电针镇痛。注入核外则无效。家兔一侧隔区或伏核内注入阳离子螯合剂CDTA(20 nmol)加强吗啡镇痛和电针镇痛。文中就Ca~(2+),Mg~(2+)作用的相似性,电针镇痛与吗啡镇痛机理的相似性,以及伏核和隔区在上述镇痛中的重要性进行了讨论。
In this paper, a small amount (10 nmol) of CaCl 2 or MgCl 2 injected into the septal area or the nucleus accumbens by chronic intracranial implantation cannula can significantly antagonize morphine analgesia and electroacupuncture analgesia. Injection into the core is invalid. The rabbit septum or nucleus accumbens into the cationic chelator CDTA (20 nmol) to enhance morphine analgesia and electroacupuncture analgesia. The similarities of the Ca ~ (2 +) and Mg ~ (2+) effects, the similarities between electroacupuncture analgesia and morphine analgesia, and the importance of nucleus accumbens and septum in the above analgesia are discussed .