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对于伯氨喹啉型药物性溶血,国内已有不少报道。在我军集体预防疟疾服药时,如果不加警惕,此病随时可能发生。现将我院遇到的4例报告如下。1979年某部在广东省高州县接收新兵152人,为集体预防疟疾服用磷酸伯氨喹啉片,每日一次,每次4片(每片含盐基13.2毫克),连服4天。在服药的第2天,有4名患者出现发热、头痛、咽痛、乏力、纳减等症状。原单位按“感冒”给予复方阿司匹林等内服,不见好转,并分别于第2～4天全部出现酱油色尿,遂转来我院。入院检查体温均在37.5°～39.5℃间,贫血面容,口唇及甲床发绀,巩膜、皮肤中度黄染,扁桃体
For primaquine-type drug hemolysis, there have been many reports. The disease can occur at any time without any vigilance when our military takes collective malaria medication. Now I encountered four hospital reports are as follows. In 1979, a ministry received 152 recruits in Gaozhou County, Guangdong Province, taking primaquine phosphate tablets for group malaria control once daily for 4 tablets (13.2 mg per tablet), for 4 consecutive days. On the second day of medication, 4 patients experienced fever, headache, sore throat, fatigue, and other symptoms. The original unit according to “cold ” to give compound aspirin and other oral administration, did not improve, and respectively in the first 2 to 4 days all appeared soy sauce urine, then transferred to our hospital. Admission examination of body temperature were between 37.5 ° ~ 39.5 ℃, anemia, lips and nail bed cyanosis, sclera, moderate yellowish skin, tonsils