作者们对6例美尼尔氏病患者经颞骨前庭神经切断术所得到的新鲜前庭神经和前庭神经节标本进行了光镜和电镜观察。病人分两组,每组三人。一组病程5～7年,呈轻度到中度低频或全频程内耳性聋,有耳鸣、耳压迫或胀满感以及典型眩晕发作,Fowler重振试验阳性,甘油试验阳性,冷热试验正常或兴奋性稍低;二组病程15～21年,患侧大多为重度全频程内耳性聋或全聋,有耳鸣、眩晕,除1例外,冷热试验兴奋性降低,甘油试验大多为阴性。另从耳健康的死者于死后20小时内开颅取颞骨、磨去内耳道壁,切取前庭神经和前庭神经节标本作同样的光镜和电镜检查以资对照。结果:光镜下对照组个别有因年龄因素所致之内髓鞘板消失外,无其他明显异常,而在病人却显示前庭神经束、神经节核周体 The authors examined the fresh vestibular and vestibular ganglia specimens from 6 cases of Meniere’s disease who underwent temporal bone vestibular neurotomy by light and electron microscopy. The patient was divided into two groups of three. A group of 5 to 7 years duration, mild to moderate low frequency or full range of the inner ear hearing loss, tinnitus, ear pressure or fullness and typical vertigo, Fowler vibration test positive, glycerol test positive, hot and cold test Normal or slightly lower excitability; two groups of 15 to 21 years duration, most of the affected side of the severe full-range or full-range deafness of hearing loss, tinnitus, dizziness, except for one exception, cold and heat test excitability decreased, glycerol test mostly negative. Another ear healthy from the deceased within 20 hours after death craniotomy take the temporal bone, grinding to the inner ear wall, cut the vestibular nerve and vestibular ganglion specimens for the same light and electron microscopy to check for control. Results: In the control group, there were no obvious abnormalities in the myelin sheath in the control group. However, in the patients, the vestibular nerve bundle and the perinuclear area of ​​the ganglion