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作者测定了20例狼疮性肾炎(LN)患者和20例正常人的尿酸化功能和血、尿渗透压。结果显示:LN患者的尿HCO3-与正常对照组无显著性差异(P>0.05);尿TA,NH4-和NAC的排泄量,LN患者中病理改变呈多灶状肾小管萎缩组(A组)显著低于对照组和局灶肾小管萎缩组(B组)(P<0.01)。
The authors measured uric aciduria and blood and urine osmolality in 20 patients with lupus nephritis (LN) and 20 normal controls. The results showed that there was no significant difference between the two groups (P> 0.05). The excretion of urine TA, NH4- and NAC, LN pathological changes were multifocal tubular atrophy A group) was significantly lower than the control group and focal tubular atrophy group (B) (P <0.01).