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近期我们用顺铂(PDD)加大剂量氨甲喋呤(MTX)腔内灌注并用四氢叶酸钙(CF)肌注,治疗胸膜恶性间皮瘤和睾丸鞘膜恶性间皮瘤术后腹腔广泛转移各1例,均获良效,报道如下。例1 患者女,34岁。咳嗽、低热伴胸痛、胸闷2月。胸片示右侧胸腔大量积液。胸腔穿刺抽出血性胸水,胸水沉渣中找到大量异型间皮细胞。胸膜活检证实为胸膜恶性间皮瘤(混合型),于1990年1月2日
Recently, we used cisplatin (PDD) to increase the dose of methotrexate (MTX) intraluminal infusion and intramuscular injection of calcium tetrahydrofolate (CF) to treat peritoneal malignant mesothelioma and testicular sheath malignant mesothelioma after extensive abdominal cavity metastasis. The cases were all well-received and reported as follows. Case 1 Female patient, 34 years old. Cough, low fever with chest pain, chest tightness in February. The chest radiograph shows a large amount of fluid in the right thoracic cavity. Thoracic puncture and hemorrhage pleural effusion, pleural sediment found a large number of abnormal mesothelial cells. Pleural biopsy confirmed as pleural malignant mesothelioma (hybrid), on January 2, 1990